Name:AITRL,MouseSynonyms:Activation-inducedTNFRmemberLigand,TNFSF18,GITRL,TL-6Description:Activation-InducibleTNF-RelatedLigand(AITRL),alsoknownasGlucocorticoid-InducedTNF-RelatedLigand(GITRL),belongstothetumornecrosisfactorsuperfamily(TNFSF).AITRLisaTypeIIsingletransmembraneproteinandshareslowconservationwithintheextracellulardomainwithotherTNFSFmembers.AITRLisexpressedonmacrophages,immatureandmaturedendriticcellsandBcells.Itsreceptor,Activation-InducibleTNFRfamilyReceptor(AITR),isexpressedonTlymphocytes,naturalkiller(NK)cells,andantigen-presentingcells.AfterbindingbyAITRL,AITRcanbereleased.AITRactivationincreasesresistancetotumorsandviralinfectionsandisinvolvedinautoimmuneandinflammatoryprocesses.Inaddition,activatedAITRincreasesTCR-inducedTcellproliferationandcytokineproductionandrescuesTcellsandNKcellsfromapoptosis.RecombinantmouseActivation-InducibleTNF-RelatedLigand(rmAITRL)producedinE.eotaxin-2在空腸和脾臟中組成型表達(dá)， 它也可以通過過敏原挑戰(zhàn)和IL-4在肺中誘導(dǎo)。Recombinant Human IFN gamma R1/IFNGR1 Protein,hFc Tag

Cas9核酸酶是一種向?qū)NA（guideRNA,gRNA）引導(dǎo)的核酸內(nèi)切酶，可催化雙鏈DNA的裂解。NLS-Cas9-EGFP在Cas9核酸酶的基礎(chǔ)上進(jìn)行改造，它在N端包含一個核定位信號(NLS)，在C端包含一個EGFP和一個6X(His)序列。當(dāng)Cas9以NLS序列表達(dá)時，Cas9RNP復(fù)合物在進(jìn)入細(xì)胞后立即定位到細(xì)胞核。不需要體內(nèi)轉(zhuǎn)錄或翻譯，提高了效率。此外，與其他系統(tǒng)相比，EGFP標(biāo)簽可作為追蹤或分類轉(zhuǎn)染細(xì)胞的報告器，通過熒光細(xì)胞分選(FACS)富集所需基因組編輯的細(xì)胞群。它降低了在基因組編輯應(yīng)用中與單細(xì)胞克隆和基因分型相關(guān)的人工和成本。產(chǎn)品特點如下：無DNA：沒有外部DNA添加；高切割效率：NLS確保Cas9蛋白高效進(jìn)入細(xì)胞核；低脫靶效應(yīng)：Cas9核酸酶的瞬時表達(dá)提高了切割的特異性；節(jié)省時間：無需轉(zhuǎn)錄和翻譯；減少勞動力：通過基于EGFP的FACS富集細(xì)胞群以進(jìn)行所需的基因組編輯。C端His標(biāo)簽增加了融合蛋白檢測方法的選擇?？蓱?yīng)用于：通過體外DNA切割篩選高效和特異性靶向gRNA。通過電穿孔或注射與特定gRNA結(jié)合時的體內(nèi)基因編輯。通過基于EGFP的FACS富集細(xì)胞群以進(jìn)行所需的基因組編輯。儲存條件-25~-15℃保存，有效期1年。Recombinant Cynomolgus CD6 Protein,His Tag（FGF-21）是FGF基因家族的成員。 基于其結(jié)構(gòu)，F(xiàn)GF-21與FGF-19和-23一起進(jìn)一步分為FGF的亞家族。

Recombinant Biotinylated Human KIR2DL1 Protein,His-Avi Tag性能參數(shù)分子別名（Synonyms）CD158A;CD158Ankat1;cl-42表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）BiotinylatedHumanKIR2DL1ProteinisexpressedfromHEK293withHistagandAvitagattheC-Terminus.ItcontainsHis22-Arg242.[Accession|P43626]分子量大?。∕olecularWeight）TheproteinhasapredictedMWof27.1kDa.Duetoglycosylation,theproteinmigratesto48-60kDabasedonSDS-PAGEresult.（Endotoxin）Lessthan1EUperμgbytheLALmethod.純度（Purity）>95%asdeterminedbySDS-PAGEandHPLC.制劑（Formulation）Lyophilizedfrom0.22μmfilteredsolutioninPBS(pH7.4).Normally8%trehaloseisaddedasprotectantbeforelyophilization.重構(gòu)方法（Reconstitution）Centrifugethetubebeforeopening.Reconstitutingtoaconcentrationmorethan100μg/mlisrecommended.Dissolvethelyophilizedproteinindistilledwater.儲存條件Theproductshouldbestoredat-25~-15℃for1yearfromdateofreceipt.2-7days,2~8°Cundersterileconditionsafterreconstitution.

Trop-2,alsoknownasepithelialglycoprotein-1antigen(EGP-1),isaproteinthatinhumansisencodedbytheTACSTD2gene.Mutationsofthisgeneresultingelatinousdrop-likecornealdystrophy,anautosomalrecessivedisordercharacterizedbyseverecornealamyloidosisleadingtoblindness.產(chǎn)品性質(zhì)別名EGP1;EGP-1;TROP2;GA733-1;gp50;T16;TACSTD2;TROP-2;M1S1;TACD2UniprotNo.P09758表達(dá)區(qū)間及表達(dá)系統(tǒng)RecombinantBiotinylatedHumanTROP-2/TACSTD2ProteinisexpressedfromHEK293cellswithHistagandAvitagattheC-terminal.ItcontainsHis27-Thr274.分子量TheproteinhasapredictedMWof30.5kDa.Duetoglycosylation,theproteinmigratesto46-55kDabasedonTris-BisPAGEresult.純度>95%asdeterminedbySDS-PAGEandHPLC活性ELISAData:ImmobilizedAnti-TROP-2Antibody,hFcTagat0.5μg/mL(100μL/well)ontheplate.DoseresponsecurveforBiotinylatedHumanTROP-2,HisTagwiththeEC50of24.1ng/mLdeterminedbyELISA.0EUper1μgoftheproteinbytheLALmethod.制劑Lyophilizedfrom0.22μmfilteredsolutioninPBS(pH7.4).Normally5%trehaloseisaddedasprotectantbeforelyophilization.雙堿性內(nèi)切酶又稱為Kex2蛋白酶、YSCF蛋白酶，在酵母體內(nèi)Kex2蛋白酶負(fù)責(zé)加工killer toxin和α-factor的前體。

Recombinant Biotinylated Human ENPP-3 Protein,His-Avi Tag性能參數(shù)分子別名（Synonyms）NPP3;E-NPP3;PD-Ibeta表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）BiotinylatedHumanENPP-3ProteinisexpressedfromHEK293withHistagandAvitagattheN-Terminus.ItcontainsLeu48-Ile875.[Accession|O14638]分子量大?。∕olecularWeight）TheproteinhasapredictedMWof99.97kDa.Duetoglycosylation,theproteinmigratesto110-130kDabasedonSDS-PAGEresult.（Endotoxin）Lessthan1EUperμgbytheLALmethod.純度（Purity）>95%asdeterminedbySDS-PAGEandHPLC.制劑（Formulation）Lyophilizedfrom0.22μmfilteredsolutioninPBS(pH7.4).Normally8%trehaloseisaddedasprotectantbeforelyophilization.重構(gòu)方法（Reconstitution）Centrifugethetubebeforeopening.Reconstitutingtoaconcentrationmorethan100μg/mlisrecommended.Dissolvethelyophilizedproteinindistilledwater.儲存條件Theproductshouldbestoredat-25~-15℃for1yearfromdateofreceipt.2-7days,2~8°Cundersterileconditionsafterreconstitution.3-6months,-85~-65℃understerileconditionsafterreconstitution.α-凝血酶（α-Thrombin）是一種高度特異性的絲氨酸蛋白酶，由凝血酶原經(jīng)蛋白水解活化而來。Recombinant Human PGF Protein,hFc Tag

在體內(nèi)，活化的X因子（Factor Xa）切割凝血酶原，釋放出活性肽并將凝血酶切割成具有催化活性的α-凝血酶。Recombinant Human IFN gamma R1/IFNGR1 Protein,hFc Tag

Coronavirusesarecommonlycomprisedoffourstructuralproteins:Spikeprotein(S),Envelopeprotein(E),Membraneprotein(M)andNucleocapsidprotein(N).TheSARS-CoV-2Sproteinisaglycoproteinthatmediatesmembranefusionandviralentry.TheSproteinishomotrimeric,witheach~180-kDamonomerconsistingoftwosubunits,S1andS2.TheRBDofSARS-CoV-2bindsametallopeptidase,angiotensin-convertingenzyme2(ACE-2).產(chǎn)品性質(zhì)別名SproteinRBD;SglycoproteinRBD;SpikeproteinRBDAccessionQHD43416.1表達(dá)區(qū)間及表達(dá)系統(tǒng)RecombinantSARS-CoV-2SpikeRBD(OmicronBA.4/BA.5/BA.5.1.3/BA.5.2)ProteinisexpressedfromExpi293withHistagattheC-terminal.ItcontainsArg319-Phe541(G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H).Recombinant Human IFN gamma R1/IFNGR1 Protein,hFc Tag

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